SPITZ nevus (juvenile melanoma) in the pediatricians practice: Clinical picture, diagnosis, prognosis and treatment

Spitz nevi (epithelioid and spindle-cell nevi) are a special group of melanocytic neoplasms with a specific clinical, dermatoscopic and histological picture. There are typical and atypical Spitz nevus. The typical Spitz nevus is more common in pediatric practice and has a benign course. Of particular interest are atypical forms that combine the characteristics of a typical Spitz nevus and melanoma. The article presents an analysis of the clinical picture, dermatoscopic, immunohistochemical, histological and genetic characteristics in various forms of Spitz nevus. The existing classification according to the metastasis risk degree is presented. The last recommendations on the tactics of managing patients with this nosology are discussed with examples of original observations. © 2021, Pediatria Ltd.. All rights reserved.

Authors
Tamrazova O.B. 1 , Sergeev V.Yu.2, 3 , Nikitaev V.G.4 , Taganov A.V. 1 , Glukhova E.A.5 , Pronichev A.N.4
Journal
Pediatriya - Zhurnal im G.N. Speranskogo
Number of issue
1
Language
Russian
Pages
166-172
Status
Published
Link
External link
DOI
10.24110/0031-403X-2021-100-1-166-172
Volume
100
Year
2021
Organizations
  • 1 People’s Friendship University of Russia, Moscow, Russian Federation
  • 2 Russian Society for Dermatoscopy and Optical Skin Diagnostics, Moscow, Russian Federation
  • 3 Department of Dermatovenereology and Cosmetology with, FSBI of Additional Professional Education «Central State Medical Academy«, Office of the President of the Russian Federation, Moscow, Russian Federation
  • 4 National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow, Russian Federation
  • 5 Network of Private Children’s Clinics «SM-Doctor,«, Moscow, Russian Federation
Keywords
Artificial intelligence; Atypical spitz nevus; Dermatoscopy; Melanoma; Spitz nevus
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