Study of plants of genus stachys on the example of Betonicaofficinalisl. Within the scientific course “pharmaceutical remake”

The paper describes a retrospective analysis of the use of common betony in traditional and modern medicine. The Stachys plants have not been used in modern domestic medicine yet. Therefore, based on the historical experience of the use of common betony in traditional medicine, we have emphasized its value as a plant with high therapeutic potential. In this study, we used the so-called “Pharmaceutical remake”, intended to revive interest in the now-forgotten objects of flora, which were previously widely used in medicine. The polyphenol structure of betony grass was studies with the use of the reverse-phase and graduate elution high-performance liquid chromatography. The presence of glycosides of diosmin, acacetin, luteolin and apigenin was established. The grass also contains hydroxycinnamic acids such as chlorogenic and rosemary acids, with the latter dominating in the polyphenol complex. The composition of plant terpenes in a hexane extraction has been studied by gas-liquid chromatography with mass spectrometric detection. It was determined that the terpenoid composition of betony is mainly represented by sesquiterpens: aromadendrene and germacrene, and monoterpenes: 3-carene and dihydrocarveol. © 2016, International Journal of Pharmacy and Technology. All rights reserved.

Authors
Novikov O.O. 1, 2 , Pisarev D.I. 1, 2 , Malyutina A.Y.2 , Zhilyakova E.T.2 , Novikova M.Y.2 , Lupina C.V.2
Publisher
International Journal of Pharmacy and Technology
Language
English
Pages
14454-14464
Status
Published
Number
2
Volume
8
Year
2016
Organizations
  • 1 Peoples’ Friendship University of Russia
  • 2 Belgorod State University
Keywords
Common betony; Pharmaceutical remake; High performance liquid chromatography; Flavonoids; hydroxycinnamic acids; Gas-liquid chromatography; Terpenoids
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