Introduction. The treatment of patients with femoral fractures is of particular relevance in modern traumatology, especially in patients with polytrauma. The treatment of such fractures is complicated by the fact that it depends not only on the nature of the fracture, but also on the general condition of the patient. Such fractures caused by high-energy trauma are usually comminuted or fragmented and are often accompanied by neuro-vascular complications, especially in the distal region. Such fractures are often accompanied by soft tissue damage.The purpose of the work was to improve the results of treatment of intra- and periarticular fractures of the distal femur in patients with poly-trauma. 82SCIENCE. EDUCATION. PRACTICEMaterials and methods. A prospective analysis of the use of con-version osteosynthesis in the treatment of 72 patients with intra- and periarticular fractures of the lower third of the femur against polytrauma according to the ISS 17-40 severity rating scale in a multidisciplinary hos-pital was performed.Results. The optimal time for conversion osteosynthesis in pa-tients with polytrauma was 5-7 days, which prevented the occurrence of traumatic shock, inflammatory complications in the postoperative period.Conclusions. The study confirmed the feasibility of conversion osteo-synthesis in the treatment of patients with intra- and periarticular fractures of the lower third of the femur. The use of the technique of transferring fixation of fragments by an external fixation apparatus to internal osteo-synthesis (conversion) contributed to a reduction in the time of inpatient treatment of patients with fractures of long bones.