Jurnal Infektologii.
Interregional public organization Association of infectious disease specialists of Saint-Petersburg and Leningrad region (IPO AIDSSPbR).
Vol. 9.
2017.
P. 80-85
Ugi Reaction Followed by Intramolecular Diels–Alder Reaction and Elimination of HCl: One-Pot Approach to Arene-Fused Isoindolinones
A one-pot procedure involving a four-component Ugi reaction followed by an intramolecular Diels–Alder reaction/HCl elimination cascade has been developed to provide rapid access to the isoindolinone framework in a diversity-oriented fashion. The scope of the process has been investigated with respect to all four components, and a comparison between the one-pot and sequential approaches is given. The possibility of a late-stage one-pot functionalization through Suzuki coupling has been explored. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Authors
Huang J.1
,
Du X.1
,
Van Hecke K. ,
Van Der Eycken E.V. ,
Pereshivko O.P.1
,
Peshkov V.A.1
Number of issue
30
Language
English
Pages
4379-4388
Status
Published
Link
Volume
2017
Year
2017
Organizations
- 1 College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Dushu Lake Campus, Suzhou, 215123, China
- 2 XStruct, Department of Inorganic and Physical Chemistry, Ghent University, Krijgslaan 281-S3, Ghent, 9000, Belgium
- 3 Laboratory for Organic and Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, University of Leuven (KU Leuven), Celestijnenlaan 200F, Leuven, 3001, Belgium
- 4 Peoples Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya street, Moscow, 117198, Russian Federation
Keywords
Cycloaddition; Diels–Alder reaction; Domino reactions; Multicomponent reactions; Nitrogen heterocycles; Ugi reaction
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SAE Technical Papers.
SAE International.
Vol. 2017-September.
2017.