Modern clinical aspects of total and specific ige evaluation

Immunoglobulin E (IgE) plays a critical role in majority of allergic diseases (AD) pathogenesis. As it is known, there are 3 types of AD in modern classification: IgE-mediated, non-IgE-mediated and mixed forms. However, increasing of total IgE (tIgE) in serum is observed in many other diseases besides allergy. Thus, as publications analysis shows, previously accepted tIgE reference levels in children’s blood should be specified in further studies. The article describes main reasons for tIgE levels increase or decrease in blood of children and adults. It also lists diseases that cause extremely high tIgE concentrations. © 2017, Pediatria Ltd. All rights reserved.

Authors
Macharadze D.S. 1
Journal
Pediatriya - Zhurnal im G.N. Speranskogo
Number of issue
2
Language
Russian
Pages
121-127
Status
Published
Link
External link
Volume
96
Year
2017
Organizations
  • 1 People’s Friendship University of Russia, Moscow, Russian Federation
Keywords
Allergic and non-allergic diseases; Children; High level of total IgE; Local IgE; Low level of total IgE; Total IgE
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/5796/
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