Лечение тяжелых форм сухого кератоконъюнктивита собак с применением аутологичной плазмы, обогащенной тромбоцитами

TREATMENT OF SEVERE FORMS OF KERATOCONJUNCTIVITIS SICCA IN DOGS USING AUTOLOGOUS PLATELET-RICH PLASMA

The material presented in this paper contains data on the use of PRP (platelet rich plasma) - autologous plasma enriched with platelets. In the treatment of severe forms of KCS(keratoconjunctivitis sicca) dogs'. The proposed method is based on the use of platelet growth factors contained in PRP [1]. Comparison of modern treatment regimens and regimens with the addition of PRP showed sufficient therapeutic efficacy of the latter in the treatment of dry keratoconjunctivitis of dogs and related various keratopathies. When using PRP as part of the complex therapy of KCS, treatment time is reduced, the rate of instillation of antibiotics, immunosuppressive drugs is reduced, the period of remission, which is persistent and prolonged, is increased. Based on the results of our study, dogs who had a severe form of KCS, receiving as part of the complex therapy also PRP, had a more intense positive dynamics and by the 30th day of treatment the degree of hydration of the anterior segment of the eye was much higher than the initial results. Against the background of standard treatment with the use of conventional therapeutic methods, the level of moisture in the anterior segment of the eye also increased, but the positive dynamics was less intense and less pronounced. Our research in the field of application of PRP in veterinary ophthalmology shows that the level of total tear production in severe forms of KCS is restored to a greater extent, compared with standard conservative treatments, it is possible to achieve maximum therapeutic effect in a shorter time. According to the results of our research, we can also say that it acts as a protector of tissue regeneration [1, 13] and due to the presence of these properties, its use is justified in various kinds of inflammatory or traumatic processes in the tissues of the anterior ocular surface.