Information value of ante- And intranatal risk factors for bronchopulmonary dysplasia in preterm newborns [Информативность анте- и интранатальных факторов риска развития бронхолегочной дисплазии у недоношенных новорожденных]

Aim of the study. To identify the leading antenatal and intranatal risk factors for bronchopulmonary dysplasia based on the analysis of their prevalence and information content Materials and methods. We performed a prospective follow-up of 124 infants of gestational age of less than 32 weeks with the classical form of bronchopulmonary dysplasia (study group). The control group included 119 newborns with gestational age of less than 32 weeks without bronchopulmonary dysplasia. The parents of the compared groups were questioned, with the following assessment of the prevalence and informative value of antenatal and intranatal risk factors. Results. The leading antenatal and intranatal risk factors for the development of bronchopulmonary dysplasia are: acute respiratory viral infection in II-III trimester, threatened miscarriage, intrauterine growth retardation, Apgar score at the 1st (3 or less) and 5th minute (5 or less), body weight of less than 1400g at birth, body length less than 36 cm at birth, cesarean section, more then 6-hours waterless period. Conclusion. The combination of these intranatal and antenatal risk factors can be attributed to a group with high risk of bronchopulmonary dysplasia. © 2019 National Academy of Pediatric Science and Innovation. All rights reserved.

Agarkov N.M.1 , Kicha D.I. 2 , Blinkov Yu.Yu.3 , Antsupov V.N.4 , Protsenko R.V.1 , Lutsenko I.V.5 , Poshivailova A.V.6
National Academy of Pediatric Science and Innovation
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  • 1 Southwest State University, Kursk, Russian Federation
  • 2 Peoples 'friendship University of Russia (RUDN University), Moscow, Russian Federation
  • 3 Kursk State Medical University, Kursk, Russian Federation
  • 4 Health Committee of Kursk Region, Kursk, Russian Federation
  • 5 Belgorod State National Research University, Belgorod, Russian Federation
  • 6 Perinatal Center of St. Joasaph Belgorod Regional Clinical Hospital, Belgorod, Russian Federation
Antenatal risk factors; Bronchopulmonary dysplasia; Children; Information value; Intranatal risk factors; Newborns; Preterm newborns
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Sharonova N.V., Ischenko A.A., Yagudaeva E.Y., Sizova S.V., Smirnova E.V., Ermakova A.Y., Sviridov A.P., Zubov V.P.
Izvestiya Vysshikh Uchebnykh Zavedenii, Seriya Khimiya i Khimicheskaya Tekhnologiya. Ivanovo State University of Chemistry and Technology. Vol. 62. 2019. P. 86-96