A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders

Objective. To study the efficacy and tolerability of the new anxyolytic peptide selank in comparison with phenazepam.Material and methods. A comparative study of the anxiolytic effect and tolerability of selank and phenazepam was carried out in 60 patients with phobic-anxiety- and somatoform disorders (F40.2—9, F41.1—9, F45.0—1 by ICD-10) were examined.Results. Pronounced anxiolytic and mild nootropic effects of selank were demonstrated. The anxiolytic effect lasted for a week after last receiving the peptide. Selank had a positive impact on the quality of life of the patients.Conclusion. The data obtained in the study extend therapeutic possibilities in the treatment of anxiety disorders. © 2014, Media Sphera. All rights reserved.

Authors
Medvedev V.E. 1, 2, 3 , Tereshchenko O.N. 1, 2, 3 , Israelyan A.Y. 1, 2, 3 , Chobanu I.K. 1, 2, 3 , Kost N.V. 1, 2, 3 , Sokolov O.Y. 1, 2, 3 , Myasoyedov N.F. 1, 2, 3
Journal
Zhurnal Nevrologii i Psihiatrii imeni S.S. Korsakova
Number of issue
7
Language
Russian
Pages
17-22
Status
Published
Link
External link
Volume
2014
Year
2014
Organizations
  • 1 Russian Peoples Friendship University, Moscow, Russian Federation
  • 2 Menthal Health Research Center, Russian Academy of Sciences, Moscow, Russian Federation
  • 3 Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russian Federation
Keywords
Anxiety disorders; Anxiolytic effect; Phenazepam; Selank
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