The purpose of the present research - a clinical estimation of mental changes at carrying out of operations interlaminar ring keratoplasty. 21 patient (7 males and 14 females) were studied. Their middle age was 36,4±9,4 years. All patients have been operated by a method interlaminar ring keratoplasty. On a current of the preoperative period all patients have been divided into 4 subgroups: without psychopathological semiology (11-52,4%), with asteno-depressive semiology (5-23,8%), with disturbing semiology (2-9,5%), with disturbing-depressive semiology (3-14,3 %). With psychopathological displays in the preoperative period (with asteno-depressive, it is disturbing-phobical, disturbing-depressive semiology) we have united patients in one group, at them neurotism level was statistically significantly above, than at patients without the psychopathological phenomena (10,7 ± 2,1 vs 14,2 ± 1,3, р ≤ 0,05). The highest neurotism level was found out in patients with disturbing-depressive reactions. Level of alarm at surveyed at the moment of inspection has made 13,2 ± 1,1 that corresponds to an average (with the tendency to low) to alarm level. Level of depression at the surveyed has made 5,7 ± 1,2, only at 3 patients it was above normal (10,1 ± 2,3). At patients with myopia high degree before operation interlaminar keratoplasty the asteno-depressive and disturbing reactions connected with personal features of patients were observed.