The differences in the estimation of depression severity by psychiatrists and patients during the combined treatment with agomelatine (A multicenter study “EMOTSIA”)

Objective: To compare the prognosis of depression severity estimated by the physician and by the patient based on the treatment outcome. Material and methods: One hundred and seven patients with depression were examined. Mental status was assessed with HАМ-D, SHAPS, CGI-S, CGI-I, PGI-S, PGI-I and VAS. A data analysis was performed. Results: There were differences in the estimation of depression severity by psychiatrists and patients. Moreover, the scores on HАМ-D and CGI-S were not consistent when assessed by psychiatrists. As the severity of depression decreased and patient’s state improved during the treatment with agomelatine (valdoxan), the assessments of the changes by the psychiatrist and the patient became similar. Conclusion: Agomelatine (valdoxan) is effective and tolerable in the treatment of depression of any severity. The differences between the psychiatrist’s and patient’s estimation of the depression severity at baseline using different psychometric scales can level the prognostic value of treatment outcome. © 2016, Media Sphera. All rights reserved.

Authors
Medvedev V.E. 1 , Retiunsky K.2 , Ovchinnikov A.A.3 , Barylnik Y.4 , Shmilovich A.A.5 , Antokhin E.6 , Usov G.M.7 , Cheremin R.A.8 , Poletsky V.M.9 , Onegin A.V.10 , Kireeva I.P.5 , Frolova V.I. 1 , Filippova N.V.4 , Antonova A.A.4 , Deeva M.A.4 , Onegina D.A.10
Journal
Zhurnal Nevrologii i Psihiatrii imeni S.S. Korsakova
Number of issue
11
Language
Russian
Pages
26-34
Status
Published
Link
External link
DOI
10.17116/JNEVRO201611611126-34
Volume
116
Year
2016
Organizations
  • 1 Russian University of People’s Friendship, Moscow, Russian Federation
  • 2 Ural State Medical University, Yekaterinburg, Russian Federation
  • 3 Novosibirsk State Medical University, Novosibirsk, Russian Federation
  • 4 Razumovsky Saratov State Medical University, Saratov, Russian Federation
  • 5 Pirogov National Research Medical University, Moscow, Russian Federation
  • 6 Orenburg State Medical University, Orenburg, Russian Federation
  • 7 Omsk State Medical Academy, Omsk, Russian Federation
  • 8 Organizatsion, Methodical and Consultation Unit for and Psychiatry And Suicidology Public Health Department, Moscow, Russian Federation
  • 9 South Ural State Medical University, Chelyabinsk, Russian Federation
  • 10 Murmansk Regional Psychoneurological Dispensary, Murmansk, Russian Federation
Keywords
Agomelatine; Depression; Scales; Severity
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