Mucoactive therapy in children: A view of a paediatrician and a pharmacologist

The article presents current ideas of mucoactive therapy in childhood from the viewpoints of a paediatrician and a pharmacologist. A classification of mucoactive drugs is offered depending on the components of the mucociliary system, on which the drugs act, the mechanisms of action and pharmacological effects . The article gives a detailed characteristic of mucolytic drugs topical from the clinical positions N-acetylcysteine, dornase alfa, hypertonic sodium chloride solution, ambroxol. Indications for administration of certain drugs in children, an algorithm of mucolytic therapy and errors at its prescription are described.