New methods of assessment of subclinical changes in the cardiovascular system in arterial hypertension

The heart is related with vascular system anatomically and functionally. Structural and functional changes in the arterial bed increase afterload on the left ventricle (LV), and can change its function, leading to the restructuring of the LV adaptation. Systolic blood pressure (SBP) in the aorta, directly reflecting the load on the LV, differs significantly from the SBP in the brachial artery due to delaying the occurrence of a reflected wave in the aorta. Left ventricular-arterial interaction is a concept that helps to understand the various options for the 〈optimal〉 functioning of the cardiovascular system, the effects of changes in the arterial bed to heart function. Methods of analysis of left ventricular-arterial interaction, clinical consequences of the breach and the effects of antihypertensive therapy are presented in the review; the results of the authors own studies are also presented.

Publisher
Stolichnaya Izdatelskaya Kompaniya
Number of issue
3
Language
Russian
Pages
317-324
Status
Published
Volume
12
Year
2016
Organizations
  • 1 Peoples' Friendship University of Russia, Miklukho-Maklaya ul. 6, Moscow, 117198, Russian Federation
Keywords
Arterial hypertension; Central arterial pressure; Left ventricular-arterial interaction; Reflected wave; Remodeling of the cardiovascular system
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/4035/
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