Immunohistochemical features of breast fibroadenomas

9 breast fibroadenomas from females of different age who had a familial history of breast cancer were immunohistochemically studied. Having the same histological structure, the tumors differed in the expression of steroid hormone receptors, in the values of proliferation marker Ki-67 and oncomarker p53. It is concluded that the study of fibroadenoma may reveal breast carcinoma risk groups.

Authors
Samoilov M.V.1, 2 , Bessmertnaya V.S.1, 2 , Babichenko I.I. 3
Number of issue
4
Language
Russian
Pages
41-43
Status
Published
Volume
69
Year
2007
Organizations
  • 1 Russian State Medical University, 117997, Moscow, Russian Federation
  • 2 Central Clinical Hospital, Russian Academy of Sciences, 117393, Moscow, Russian Federation
  • 3 Russian University of People's Friendship, 117198, Moscow, Russian Federation
Keywords
Ki 67 antigen; protein p53; steroid receptor; tumor marker; adolescent; adult; article; breast tumor; chemistry; female; fibroadenoma; human; immunohistochemistry; pathology; Adolescent; Adult; Breast Neoplasms; Female; Fibroadenoma; Humans; Immunohistochemistry; Ki-67 Antigen; Receptors, Steroid; Tumor Markers, Biological; Tumor Suppressor Protein p53
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