The effect of antibiotic therapy on embryotropic antibodies in women

Embriotropic antibodies (e-Ab) scrum contents were analysed in 29 serum samples obtained from women suffering with primary lues. Before treatment the content of e-Ab against MBP, S100, ACBP14/18, and MP65 were markedly elevated in 28 samples. Two injections of Retarpen (2,5 mln Units with one week interval) were enough for effective treatment of lues. At the same time treatment caused deep and reversible inhibition of e-Ab production. One or two months later the levels of e-Ab returned to normal values in 21% of women, in 52% patients the hypoproduction, and in 27% the hyperproduction of e-Ab were noted. Deviations of e-Ab production after effective retarpen treatment suggest the existence of additional reasons which may influence e-Ab production, and necessity of additional diagnostic and curative measures for such women during pregravidal period.

Authors
Morozov S.G.1, 2 , Poletaev A.B.3 , Radzinsky V.E. 4 , Protsenko A.N.4 , Korgenevskii D.A.2
Editors
-
Publisher
-
Number of issue
2
Language
Russian
Pages
-
Status
Published
Department
-
DOI
-
Number
-
Volume
47
Year
2001
Organizations
  • 1 Municipal Hospital No. 29, Committee for Health, Moscow, Russian Federation
  • 2 Orekhovich Inst. of Biomed. Chem., RAMS, Moscow, Russian Federation
  • 3 Fund Chernobyl-Test, Moscow, Russian Federation
  • 4 Dept. of Obstetrics and Gynecology, Peoples Frendship University, Moscow, Russian Federation
Keywords
Antibiotic therapy; ELISA; Embryotropic antibodies
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/299/