Independent diagnostic value of microalbuminuria and calculated glomerular filtration rate in patients with arterial hypertension for detection of subclinical renal involvement

In 734 patients with arterial hypertension without established diseases of cardiovascular system (including 158 patients with diabetes mellitus) we compared various methods of assessment of functional state of the kidney (microalbuminuria, creatinine, calculation of creatinine clearance and glomerular filtration rate) for detection of subclinical renal involvement and assessment of cardiovascular risk. We showed that determination of microalbuminuria and calculation of glomerular filtration rate (MDRD equation) had independent and mutual complementary diagnostic value, and allowed to identify patients with pathogenetically different renal lesions, reflected proteinuric and nonpoteinuric mechanisms of progression of nephropathy in arterial hypertension with and without diabetes mellitus.

Journal
Publisher
KlinMed Consulting
Number of issue
4
Language
Russian
Pages
12-17
Status
Published
Volume
50
Year
2010
Organizations
  • 1 Russian University of Peoples Friendship, ul. Vavilova 61, 117292 Moscow, Russian Federation
Keywords
Calculated glomerular filtration rate; Microalbuminuria; Nonproteinuric nephropathy; Subclinical renal involvement
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/2647/
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