PREVALENCE OF HEART FAILURE AMONG HOSPITALIZED PATIENT WITH T2D: RESULTS OF A PROSPECTIVE OBSERVATIONAL MULTICENTER STUDY (CREDO); [ОЦЕНКА РАСПРОСТРАНЕННОСТИ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ У ПАЦИЕНТОВ С САХАРНЫМ ДИАБЕТОМ 2 ТИПА, ГОСПИТАЛИЗИРОВАННЫХ В МНОГОПРОФИЛЬНЫЕ СТАЦИОНАРЫ: РЕЗУЛЬТАТЫ ПРОСПЕКТИВНОГО НАБЛЮДАТЕЛЬНОГО МНОГОЦЕНТРОВОГО ИССЛЕДОВАНИЯ (КРЕДО)]

BACKROUND: Heart failure (HF) is in the first place in the structure of cardiovascular death in patients with type 2 diabetes mellitus (T2D). One of the factors determining the prognosis of patients with this pathology is hospitalization. The difficulties of managing patients are related to the heterogeneity of the population. In some cases, HF in patients with T2D remains undiagnosed, and data on the true frequency of HF in patients with T2D and their clinical and laboratory characteristics in real clinical practice remain limited. AIM: To assess the prevalence of HF, clinical and demographic characteristics and therapy profile in patients with T2D admitted to multidisciplinary hospitals. MATERIALS AND METHODS: A prospective observational multicenter study was conducted at the city clinical hospitals of the Moscow. For the period from August 2022 to April 2023, data from patients with T2D were analyzed. Data collection was carried out at one visit. The study design did not involve any intervention in routine clinical practice, including the choice of diagnostic method or treatment. RESULTS: The study included 445 patients in accordance with the main inclusion criteria - T2D, age over 50 years, duration of T2D more than 3 years. The incidence of HF in patients with type 2 diabetes at discharge was 76.6%. The diagnosis of HF was confirmed in 48.7% (n=217), newly diagnosed HF occurred in 27.9% (n=124) of cases, in 12.6% of patients (n=56) the diagnosis of HF was withdrawn, in 10.8% (n=48) of cases the diagnosis of HF was not established. The frequency of prescribing drugs at discharge was iSGLT-2 — 77.3% (n=344), statins — 86.7% (n= 386), MRAs — 23.1% (n=103), diuretics — 46.1% (n=205). CONCLUSION: 76.6% of patients with T2D admitted to multidisciplinary Moscow hospitals were diagnosed with HF at discharge. The results obtained confirm the possibility of detecting HF and initiating cardioprotective therapy at the hospital stage, using inpatient clinical diagnostic examination, and patients with type 2 diabetes lasting more than 3 years and aged over 50 years can be classified as a high risk group for developing HF. © 2024 Russian Association of Endocrinologists. All rights reserved.

Authors
Antsiferov M.B. , Kobalava Z.D. , Demidova T.Y. , Markova T.N. , Tolkacheva V.V. , Morgunov L.Y. , Andreeva A.V. , Pashkova E.Y. , Khaziakhmetova M.R. , Samburova E.S. , Vedyashkina S.G. , Mkrtumyan A.M. , Petunina N.A. , Serebrov A.N. , Deeva T.M. , Karaeva A.Y.
Publisher
Russian Association of Endocrinologists
Number of issue
1
Language
Russian
Pages
4-14
Status
Published
Volume
27
Year
2024
Organizations
  • 1 Endocrinological Dispensary, Moscow City Health Department, Moscow, Russian Federation
  • 2 V.V. Vinogradov Hospital, Moscow, Russian Federation
  • 3 RUDN University, The Peoples’Friendship University of Russia, Moscow, Russian Federation
  • 4 Pirogov Russian National Research Medical University, Moscow, Russian Federation
  • 5 V.P. Demikhov Hospital, Moscow, Russian Federation
  • 6 City Clinical Hospital №52, Moscow, Russian Federation
  • 7 V.V. Veresaev Hospital, Moscow, Russian Federation
  • 8 A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russian Federation
  • 9 A.K. Eramishantsev Hospital, Moscow, Russian Federation
  • 10 S.P. Botkin Hospital, Moscow, Russian Federation
  • 11 D.D. Pletnev Clinical Hospital, Moscow, Russian Federation
  • 12 L.A. Vorohobov City Clinical Hospital, Moscow, Russian Federation
  • 13 I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation
Keywords
chronic heart failure; ejection fraction; hospitalization; NT-proBNP; type 2 diabetes

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