Based on the study of the proposals received in 2020–2021 from the authorized bodies of the Eurasian Economic Union member states to change the rates of import duties on certain categories of goods received, the paper reveals the geographical, industry, and target features of customs and tariff measures of regulation of foreign trade activity of the EAEU. During the studied period, 90% of the measures were aimed at reducing or establishing zero rates of import duties. It was found that the most significant number of proposals accounted for goods of the engineering, metallurgical, and chemical industries. The authors investigated the impact of sanction restrictions on the application of measures of customs and tariff regulation in the context of the analysis of key measures that contribute to the improvement of macroeconomic stability of the EAEU member countries. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2023.