Purpose of the study: to identify clinical and anamnestic features, as well as assess the quality of life, degree of depression and anxiety in infertile patients with benign neoplasms of the uterus and ovaries. Materials and methods. The study involved 498 infertile patients with benign tumors of the uterus and ovaries: group I consisted of 202 patients with uterine fibroids; Group II - 256 women with benign ovarian tumors. The comparison group consisted of 40 fertile patients. Results. Analysis of the anamnesis of infertile patients with benign neoplasms of the uterus and ovaries revealed a number of clinical and anamnestic factors that reduce reproductive function and quality of life: early sexual debut, inflammatory diseases of the pelvic organs; sexually transmitted infections; dysmenorrhea, hypermenorrhea, dyspareunia, chronic pelvic pain, depression and anxiety.