Reaction of 2-Hydroxy-5-methylacetophenone Chalcones with Guanidine in the Presence of Hydrogen Peroxide

Two chalcones derived from 2-hydroxy-5-methylacetophenone reacted with guanidine in the presence of hydrogen peroxide to give 4,6-diaryl-2-aminopyrimidine or flavonol derivative, depending on the initial chalcone structure. The products were identified by NMR spectroscopy and X-ray analysis. Probable reaction paths were proposed.

Authors
Mamedov I.G.1 , Khrustalev V.N. 2, 3
Number of issue
9
Language
English
Pages
1637-1640
Status
Published
Volume
59
Year
2023
Organizations
  • 1 Faculty of Chemistry, Baku State University, 1148, Baku, Azerbaijan
  • 2 Peoples' Friendship University of Russia
  • 3 Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991, Moscow, Russia
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